School of Medicine
University of Patras
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Personel - TZELEPI VA.

TZELEPI VASILIKI, Associate Professor

TZELEPI VASILIKI

Sector: Division of Clinical Laboratories

Clinic/Laboratory: Department of Pathology

Knowledge Subject: Pathology

Research Area: Carcinogenesis, Prostate Cancer, Epigenetics

Department of Pathology, University Hospital of Patras, 2nd floor

+302613604082 btzelepi@upatras.gr

Office hours

Monday and Wednesday, 13:00-14:00

Undergraduate Courses

Selected Publications

Aparicio A, Tzelepi V, Araujo JC, Guo CC, Troncoso P, Logothetis CJ, Navone NM, Maity SN. Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient’s tumor: Morphological, immunohistochemical, and gene expression profiles. Prostate 2010, 71: 846-856, 2010

Tzelepi V, Karlou M, Wen S, Hoang A, Logothetis C, Troncoso P, Efstathiou E. Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signaling. Histopathology 58:1037-1047, 2011

Tzelepi V, Efstathiou E, Wen S, Troncoso P, Karlou M, Pettaway CA, Pisters LL, Hoang A, Logothetis CJ, Pagliaro LC. Persistent, biologically meaningful prostate cancer after one year of androgen ablation and docetaxel treatment. J Clin Oncol 29:2574-2581, 2011

Tzelepi V, Zhang J, Lu JF, Kleb BN, Wu G, Hoang A, Efstathiou E, Sircar K, Navone N, Troncoso P, Liang SL, Logothetis CJ, Maity SN, Aparicio AM. Modeling a lethal prostate cancer variant with small cell features. Clin Cancer Res 18:666-677, 2012

Aparicio A, Tzelepi V. Neuroendocrine (Small-Cell) Carcinomas: Why They Teach Us Essential Lessons About Prostate Cancer. Oncology (Williston Park). 28(10), 2014

Tzelepi V. Editorial: Personalized cancer treatment. Curr Mol Pharmacol 7:2-3, 2014

Tzelepi V, Logotheti S, Efstathiou E, Troncoso P, Aparicio  A.  Sakellakis M, Hoang A, Perimenis P, Melachrinou M, Logothetis C, Zolota V. Epigenetics and Prostate Cancer: Defining the Timing of DNA Methyltransferase Deregulation During Prostate Cancer Progression.  Pathology 52:218-227, 2020

Tzelepi V, Grypari IM, Logotheti S, Kontogiannis S, Kallidonis P, Melachrinou M, Zolota V. Contemporary Grading of Prostate Cancer: The Impact of Grading Criteria and the Significance of the Amount of Intraductal Carcinoma. Cancers (Basel) 29;13(21):5454, 2021

Grypari IM, Zolota V, Tzelepi V. Radical or Not-So-Radical Prostatectomy: Do Surgical Margins Matter? Cancers (Basel).  21;14(1):13, 2021

Milidaki F-T, Sakellaraki P, Papakonstantinou E, Zolota V, Tzelepi V. Molecular pathways in colorectal cancer. Achaiki Iatriki 40 (4):1-14, 2021

Grypari IM, Logotheti S, Zolota V, Troncoso P, Efstathiou E, Bravou V, Melachrinou M, Logothetis C, Tzelepi V. The protein arginine methyltransferases (PRMTs) PRMT1 and CARM1 as candidate epigenetic drivers in prostate cancer progression. Medicine (Baltimore). 10;100(36):e27094,  2021

Destouni AC, Lazaris M, Tzelepi V. Cribriform Patterned Lesions in the Prostate Gland with Emphasis on Differential Diagnosis and Clinical Significance Cancers 14 (13), 3041, 2022

Soundararajan R, Viscuse P, Pilie P, Liu J, Logotheti S,  Fernández CL, Lorenzini D, Hoang A, Lu W, Solis Soto LM, Wistuba II, Xu M, Song X, Shepherd PDA, Navone NM, R. Tidwell SS, Lozano G, Logothetis C, Zhang J, Long JP, Estecio MR, Tzelepi V, Aparicio A Genotype-to-Phenotype Associations in the Aggressive Variant Prostate Cancer Molecular Profile (AVPC-m) Components Cancers 14 (13), 3233, 2022

Grypari IM, Pappa I, Papastergiou T, Zolota V, Bravou V, Melachrinou M, Megalooikonomou V, Tzelepi V. Elucidating the role of PRMTs in prostate cancer using open access databases and a patient cohort dataset. Histology and Histopathology, 18513, 2022

Selected Presentations

‘Health Promotion- History of MDACC- Overview of Carcinogenesis and Prostate Cancer’ Transylvania University, November, 2, 2010, Lexington, KY, USA

‘Slide Seminar in GYN Pathology’ Ioannina University Courses in Pathology, 31 May - 3 June 2011, Ioannina, Greece

‘Histochemical and immunohistochemical markers for testicular tumours’  2014 Histopathology Study Day, 29 April, 2014 Galway, Ireland

‘Interesting cases in neoplastic endometrial and ovarian pathology’ Ioannina University Courses in Pathology, Gynecological Pathology-Oncology. Slide Seminar III: Pitfalls in GΥΝ Pathology – Oncology. 13 April, 2019, Ioannina, Greece

‘From tissue analysis to clinical phenotype’ 14th Update on the Management of GU Malignancies, 1 November 2019, Houston, TX, USA