School of Medicine
University of Patras
>University of Patras



Sector: Division of Basic Medical Sciences II

Clinic/Laboratory: Department of Anatomy


Research Area: • Congenital anomalies of the genitourinary system• Basic and clinical research in Prostate Cancer (angiogenesis, lymphangiogenesis, apoptosis, differentiation and sex hormone receptors, retinoids).• Basic and clinical research in Andrology (Erectile dysfunction and Infertility)• Basic and clinical research in Pelvic Floor anatomy (voiding dysfunction ,BOO, detrusor overactivity, surgical correction)


Summary of Curriculum Vitae

Kostis Gyftopoulos was born in Patras, Greece. He received his Diploma in Medicine at the University of Patras Medical School in 1992. He afterwards specialized in General Surgery In Aegion Hospital and continued with his training in the specialty of Urology in Rion University Hospital, Patras, Greece. He completed his PHD thesis at the University of Patras Medical School in 1999. He worked as a Clinical Fellow in Paediatric Urology under the European Association of Urology Scholarship Programme in Southampton University, Dept. of Paediatric Urology, Southampton, UK. He worked as a specialist in Urology at the Chios Regional Hospital and the 401 Army Hospital during his army service. He then received a scholarship from the ESPU program in Paediatric Urology at the Erasmus University Hospital, Rotterdam, the Netherlands. In 2003 he was appointed Lecturer in Anatomy at the Department of Anatomy at the University of Patras Medical School. He currently holds the position of Professor in Clinical and Surgical Anatomy at the Department. He has numerous publications in peer-reviewed journals with over 1500 citations and has been invited as a speaker in many congresses and scientific meetings. He serves as reviewer in many peer-reviewed journals (Urology Annals, European Urology, International Journal of Applied and Basic Medical Research, Educational Research, Hellenic Urology., Universal Journal of Education and General Studies (UJEGS), Advances in Sexual Medicine, Cell and Tissue, Case Reports in Medicine etc). He is also Editor/editorial staff in several electronic journals (Lead Faculty in Urology – WebMedCentral, Member Editor in Global Advanced Research Journal of Educational Research and Review, Editorial Board in Advances in Urology). He is member of many scientific societies (European Association of Urology, Εndourological Society – associate member, European Society for Paediatric Urology – associate member, Council Member in the World Federation of Societies for Paediatric Urology (WOFSPU) and International Pediatric Endosurgery Group (IPEG).

Undergraduate Courses

Postgraduate Courses

Basic Medical Sciences Postgraduate Programme, University of Patras

Medical & Radiation Physics Postgraduate Programme, University of Patras

Biomedical Engineering Postgraduate Programme, University of Patras

 Informatics for Life Sciences Postgraduate Programme, University of Patras

Clinical and Surgical Anatomy Postgraduate Course,, Democritus University of Thrace

Surgical Sciences Postgraduate Programme, University of Crete

Selected Publications

Cellular distribution of retinoic acid receptor-α in benign hyperplastic and malignant human prostates. Comparison with androgen, estrogen and progesterone receptor status. K. Gyftopoulos, G. Sotiropoulou, I. Varakis, G.A. Barbalias. Eur. Urol. 38: 323-330, 2000.

 • Immunohistochemical detection of retinoic acid receptor-a in prostate carcinoma: Correlation with proliferative activity and tumor grade. K. Gyftopoulos, P. Perimenis, G. Sotiropoulou – Bonikou, G. Sakellaropoulos, I. Varakis and G.A. Barbalias. International Urology and Nephrology 32: 263-269, 2000.

 • Effect of subinguinal varicocelectomy on sperm parameters and pregnancy rate: A two-group study. P. Perimenis, S. Markou, K. Gyftopoulos, A. Athanasopoulos, G. Barbalias. European Urology, 39: 322-325, 2001.

• Cyclin E and Ki67 (MIB1) as markers of proliferative activity in human prostate cancers: an immumohistochemical study. K. Gyftopoulos, P. Perimenis, P. Ravazoula, G.A. Barbalias. Urologic Oncology, 6: 249-253, 2001

• The effects of finasteride and cyproterone acetate on hematuria associated with benign prostatic hyperplasia: A prospective, randomised, controlled study. P. Perimenis, K. Gyftopoulos, S. Markou, G. Barbalias. Urology, 59 (3): 373-377, 2002.

 • Bladder dysfunction and the role of urodynamic studies in boys with posterior urethral valves. R. Nijman, K. Gyftopoulos, K. Wolffenbuttel Progr Pediatr Urol Vol 4, 74-93, 2002.

• Clinical and embryological aspects of penile duplication and associated anomalies. K. Gyftopoulos, K. Wolfenbuttel, R. Nijman. Urology 60 (4): 675-679, 2002

 • Combination treatment with an alpha-blocker plus an anticholinergic for bladder outlet obstruction: a prospective, randomized, controlled study. Athanasopoulos A, Gyftopoulos K, Giannitsas K, Fisfis, Perimenis P, Βarbalias G. Journal of Urology, 169(6): 2253-6, 2003

• Clinical correlation of prostatic lithiasis with chronic pelvic pain syndromes in young adults. Geramoutsos, K. Gyftopoulos, P. Perimenis, V. Thanou, D. Liagka, D. Siamblis, G. Barbalias. European Urology, 45: 333-338, 2004

 • Dyspareunia due to short frenulum: the “pull and burn” method. Κ. Gyftopoulos. J Sexual Medicine 2009, 6 (9): 2611-2614.

• Increased expression of Endothelin-1 and its receptors in varicocele. A immunohistochemical study. Gyftopoulos, C. Chondrogianni, E.Papadaki. Fertility & Sterility 2011, 95 (8): 2554-2556.e2

• The angiogenic switch for vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) in prostatic carcinoma; correlation with microvessel density, androgen receptor content and Gleason grade. Gyftopoulos K, Vourda K, Sakellaropoulos G, Perimenis P, Athanasopoulos A, Papadaki E. Urologia Internationalis 2011, 87 (4): 464-469.

 • Efficacy and preoperative prognostic factors of the autologus fascia rectus sling for the treatment of female stress urinary incontinence. Athanasopoulos, K. Gyftopoulos, E McGuire. Urology, 2011, 78 (5): 1034-1038.

 • The efficacy and safety of topical EMLA cream application for minor surgery of the penis. Kostis Gyftopoulos. Urology Annals 2012, 4 (3): pp. 145-149

• The expression of Vascular Endothelial Growth Factor-C correlates with lymphatic microvessel density and lymph node metastasis in prostate carcinoma. A immunohistochemical study. Lilis Ioannis, Papadaki Helen, Kourea Helen, Gyftopoulos Kostis. Urology Annals. 2014 Jul; 6(3):224-30

The aberrant urethral meatus as a possible aetiological factor of recurrent post-coital urinary infections in young women. K. Gyftopoulos. Medical Hypotheses 2018 113; 6-8.

The expression of p-mTOR and COUP-TFII correlates with increased lymphangiogenesis and lymph node metastasis in prostate adenocarcinoma. I.Lilis, I.Giopanou, H. Papadaki, K. Gyftopoulos. Urologic Oncology. 2018 Jun;36(6):311.e27-311.e35

Expression of EMT inducers integrin-linked kinase (ILK) and ZEBl in phyllodes breast tumors is associated with aggressive phenotype. I. Akrida, S. Nikou, K. Gyftopoulos, M. Argentou, S. Kounelis, V. Zolota, V. Bravou, H Papadaki. Histol Histopathol. 2018 Sep;33(9):937-949.

Meatal stenosis after surgical correction of short frenulum. Is the “pull and burn” method the way to go?  K. Gyftopoulos. Urol Ann. 2018;10(4):354-357.

Clinical implications of the anatomical position of the urethra meatus in women with recurrent post-coital cystitis: a case-control study. K. Gyftopoulos, M. Matkaris, K. Vourda, G. Sakellaropoulos.  Int Urogynecol J. 2019 Aug;30(8):1351-1357.