Paediatric & Reproductive Endocrinology
Semester 8th ()
Hours Teaching 0 hours, Laboratory 0 hours, Tutorial 0 hours , Clinical Training 25 hours (per week)
Teachers
Description
- The development of reproductive function throughout life is analyzed.
- Sexual diversity and complementarity as well as disorders concerning sex differentiation and their implications are elaborated.
- Disorders of reproductive function during childhood and puberty and their relation to disorders during adulthood and subfertility are expounded.
- Genotypic disorders underlying phenotypic disorders of sex differentiation are presented through examples.
- During the laboratory, basic molecular techniques for the detection of gene mutations are amplified and their application is analyzed.
- The physiology of sexuality and the significance of its disorders are expounded.
Curriculum
- Development of Reproduction in living creatures (1 hour)
- Sexual differentiation (4 hours). Diagnostic and therapeutic approach
- Physiology-physiopathology
- Cases concerning children
- Surgical management
- Cases concerning adults
- The sexual component of personality
- Paraphilias
- Syndromes of resistance to hormones (1 hour)
- Congenital adrenal hyperplasia (1 hour)
- Puberty disorders (3 hours)
- Premature adrenarche
- Precocious puberty
- Delayed puberty
- Hypothalamic amenorrhea (1 hour)
- Hyperandrogenism (2 hours)
- PCOS: Pathogenesis
- PCOS: Clinical and therapeutic approach
- Subfertility (2 hours)
- Cytogenetics (1 hour)
- Molecular Endocrinology and clinical applications (4 hours)
- Laboratory of Paediatric Endocrinology (4 hours). Methods and techniques:
- DNA extraction and sequencing,
- PCR, RT-PCR,
- Western Immunoblotting,
- Tissue cultures,
- BrDu incorporation,
- Cell growth curves,
- Growth hormone deficiency and Laron syndrome,
- Childhood obesity
- Sexuality (3 hours)
- Male sexual function
- Female sexual function
- Anatomic anomalies and sexual dysfunction in adolescence
- Transexuals (2 hours)
- Sex and the Human Brain
- Clinical and Therapeutic approach