School of Medicine
University of Patras
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Personel - SYGGELOS SP.

SYGGELOS SPYROS, Associate Professor


Sector: Division of Basic Medical Sciences II

Clinic/Laboratory: Department of Anatomy

Knowledge Subject: ANATOMY

Research Area: Pathobiology of arthritis, osteoporosis and aseptic loosening of joint-replacement implants.

Panepistimioupolis Patron, Preclinical Research Building, Dept. of Anatomy-Histology-Embryology. 2nd floor

2610969196 2610969178

Summary of Curriculum Vitae

  • Medical education: From October 1989 up to June of 1995, Medical school of University of Patras.
  • Specialty in Orthopaedics and Traumatology: In 2006, after one year training in general surgery, one year in Paediatric Orthopaedics and four years training in the Orthopaedic Department of University of Patras
  • Doctoral Diploma: In 2005, with an ‘Excellent’ grade, in Medical school of University of Patras. The topic of my thesis was: «Metalloproteinases and their tissue inhibitors in periprosthetic tissues of loosened components of hip and knee replacements. Effect of non-steroidal anti-inflammatory drugs on their production and on cytokine and PGE2 production».
  • Fellowship in Julius-Maximilians University of Wurzburg (GERMANY): From 09/01/06 up to 07/07/06. Main topics were hip, knee and shoulder replacements.
  • Fellowship in Orthopaedic trauma: Heartlands Hospital in Birmingham (UK) from 01/09/2009 up to 31/01/2010
  • Fellowship in Lower Limb Arthroplasty: University hospital of Coventry and Warwickshire from 01/03/2010 up to 31/12/2010
  • Current Position: From 03/01/2012 lecturer in the department of Anatomy-Histology-Embryology of University of Patras.

Undergraduate Courses

Selected Publications

  1. S. Α. Syggelos, S. Eleftheriou, E. Giannopoulou, E. Panagiotopoulos, A. Aletras. «Gelatinolytic and Collagenolytic Activity in Periprosthetic Tissues from
    Loose Hip Endoprostheses»JOURNAL OF RHEUMATOLOGY, 28 (6): p. 1319-1329, June 2001
  2.  G.B. Kasimatis, S. A. Syggelos, C. Matzaroglou, E. Panagiotopoulos, E. Lambiris, Ch. Kalogeropoulou.
    «False-negative computer tomographic scan after a hyperextension dislocation injury of the cervical spine: A nearly missed diagnosis». AMERICAN JOURNAL OF EMERGENCY MEDICINE, Vol. 24 (2) p.p. 244-247, March 2006.
  3. P. Dimakopoulos, A. Panagopoulos, S. A. Syggelos, E. Panagiotopoulos, E. Lambiris  «Double-Loop Suture Repair for Acute Acromioclavicular Joint Disruption».
    AMERICAN JOURNAL OF SPORTS MEDICINE, Vol. 34, No 7, p.p. 1112-1119, July 2006.
  4. Syggelos S.A., Giannopoulou E., Gouvousis P.A., Andonopoulos A.P., Aletras A.J., Panagiotopoulos E.
    <<In vitro effects of non-steroidal anti-inflammatory drugs on cytokine, prostanoid and matrix metalloproteinase production by interface membranes from loose hip or knee endoprostheses.>>
    OSTEOARTHRITIS AND CARTILAGE. 15(5):531-42, May 2007
  5. Megas P, Syggelos  S A , Kontakis G, Giannakopoulos  A, Skouteris G,  Lambiris E, Panagiotopoulos E <<Intramedullary nailing for the treatment of aseptic femoral shaft non-unions after plating failure: Effectiveness and timing>> Injury. 2009 Jul;40(7):732-7.
  6. Spyros A. Syggelos,  Alexios J. Aletras, Ioanna Smirlaki,  and Spyros S. Skandalis  <<Extracellular Matrix Degradation and Tissue Remodeling in Periprosthetic Loosening and Osteolysis: Focus on Matrix Metalloproteinases, Their Endogenous Tissue Inhibitors, and the Proteasome>> Review Article
    BioMed Research International Volume 2013 (2013), Article ID 230805