School of Medicine
University of Patras
>University of Patras



Sector: Division of Surgery

Clinic/Laboratory: Department of Otorhinolaryngology

Knowledge Subject: Otorhinolaryngology - Head and Neck Surgery

Research Area: I. Carcinogenesis of the upper airway 1. Study of the biochemical changes of different biomarkers (proteins/genes/chromosomes) in various cancers of the upper aerodigestive tract. 2. Investigation of the deregulation of signaling pathways in SCCHN. 3. Early detection of head-neck tumors. II. Pathogenesis of chronic rhinosinusitis and nasal polyps 1. Correlation between the development of nasal polyps and the metabolism of various biomarkers in the respiratory epithelium. III. Detection and identification of head and neck neoplastic lesions in real time, using an innovative medical device '(acronym: i-MaD)

+30 2613 603274, +30 2613 603285 +30 2610 993986

Download Curriculum Vitae

Summary of Curriculum Vitae






Patras – April 2021








Birthdate:                                           08/09/1965

Birthplace:                                          Dortmund, Germany

Nationality:                                        Greek

Marital status:                                   Married - three children

Current post:                                     Professor of Otorhinolaryngology-Head and Neck Surgery

                                                            University of Patras Medical School

                                                            Rion-Patras, GREECE


Home address:                                   Ampelonon str. 21 - Ovria - Patras 265 00 GREECE

Contact numbers                               + 30610 – 999978 (hospital)

+ 30610 – 525441 (home)

Mob: +30 6977-642835










1990: M.D. – University of Patras Medical School, Patras, Greece

1999: Title of Medical Specialty in Otorhinolaryngology-Head and Neck Surgery 1999: Title of PhD - Thesis on “The significance of tumor markers levels in squamous cell carcinoma of the head and neck”, University of Patras Medical School, Patras, Greece

2000 - present: Consultant ENT Surgeon, ENT Department, University Hospital of Patras

2003: Clinical Fellow in Head and Neck Oncologic and Thyroid Surgery (1/3/2003 – 7/3/2003: Clinical fellowship, ENT Department, Queen Elizabeth University Hospital, Birmingham, UK)

2006: Lecturer of Otorhinolaryngology-Head and Neck Surgery, University of Patras Medical School, Patras, Greece

2010: Assistant Professor of Otorhinolaryngology-Head and Neck Surgery, University of Patras Medical School, Patras, Greece

2012: Clinical Fellow in Laryngology: Laser Microsurgery, Phonosurgery and Transoral Robotic Surgery (1/10/12-10/1/13: Clinical fellowship, ENT Department, University of Louvain, Yvoir, Belgium)

2017: Associate Professor of Otorhinolaryngology-Head and Neck Surgery, University of Patras Medical School, Patras, Greece

2021: Professor of Otorhinolaryngology-Head and Neck Surgery, University of Patras Medical School, Patras, Greece



  • Since 1990 I continuosly teach and train medical students and ENT residents of our Department.
  • I have also participated, either as Supervisor or as a Member of the Advisory Committee in 25 PhD thesis and 11 MSc thesis, carried out at the Medical School of the University of Patras
  • I have participated as a Speaker, Tutor or Trainee in many seminars, symposia and courses and I have attended numerous Greek and international congresses
  • I participate as an Organizer, Trainer and Speaker in three different MSc programms
  • ‘Diseases of the Nose, Skull Base and Face’ (University of Patras, and National and Kapodistrian University of Athens)
  • ‘Public Health’ (University of Patras)
  • ‘Rhinology - Rhinosurgery’ (University of Thrace, Aristotelion University of Thessaloniki, University of Thessaly, University of Crete)
  • I am a member of various Medical Societies including Panhellenic Medical Association, Panhellenic Association of Otorhinolaryngology-Head and Neck Surgery, European Rhinologic Society, Society of Robotic Surgery (SRS), etc.
  • My main clinical and research interests concern Head and Neck and Thyroid Surgery, Laryngological and Rhinological Surgery, Laryngeal and Head and Neck Carcinogenesis, Chronic Rhinosinusitis and Nasal Polyposis Development
  • Publications – articles in English literature: 120
  • Publications – articles in Greek literature: 15
  • Presentation of 110 studies in International and Greek conferences


Undergraduate Courses

Selected Publications

  1. Goumas PD, Mastronikolis NS, Mastorakou AN, et al. Evaluation of TATI and CYFRA 21-1 in patients with Head and Neck Squamous Cell Carcinoma. ORL J Otorhinolaryngol Relat Spec 1997;59:106-114. 
  2. Mastronikolis NS, Fitzgerald D, Owen C, et al. The management of squamous cell carcinoma of the neck. The Birmingham- UK experience.  Eur J Surg Oncol 2005;31(5):461-466 
  3. Mastronikolis NS, Stathas T, Papadas TA, et al. Voice restoration after total laryngectomy using Provox 2 (generation II) prosthesis: our experience. Eur Rev Med Pharmacol Sci 2008;12(5):327-30
  4. Mastronikolis NS, Papadas TA, Goumas PD, et al. Laryngeal Tumors: an overview. Atlas Genet Cytogenet Oncol Haematol. December 2008 (on-line).
  5. Mastronikolis NS, Stathas Th, Naxakis SS, et al. Necrotizing fasciitis of the head and neck: report of 5 cases and review of the literature Eur Rev Med Pharmacol Sci 2010; 14(2):123-134
  6. Kalathas D. Triantaphyllidou IE, Mastronikolis NS, et al. The chondroitin/dermatan sulfate and modifying enzymes in laryngeal cancer: expressional and epigenetic studies. Head Neck Oncol 2010 Oct 7;2:27
  7. Mastronikolis NS, Remacle M, Kiagiadaki D, et al. Medialization thyroplasty for voice restoration after transoral cordectomy. Eur Arch Otorhinolaryngol. 2013 Jul;270(7):2071-8
  8. Mastronikolis NS, Remacle M, Biagini M, et al. Wendler glottoplasty: an effective pitch raising surgery in male-to female transsexuals. J Voice 2013 Jul;27(4):516-22 . 
  9. Mastronikolis NS, Tsiambas E, Papadas TA, et al. mTOR deregulation in oral cavity squamous cell carcinoma. J BUON. 2017 May-Jun;22(3):610-613.
  10. Mastronikolis NS, Rigopoulos DN, Tsiambas E, et al. IGF/IGFR and diabetes mellitus in head and neck squamous cell carcinoma patients. J BUON. 2017 Sep-Oct;22(5):1361-1362
  11. Mastronikolis NS, Tsiambas E, Papadas TA, et al. Deregulation of PTEN Expression in Laryngeal Squamous Cell Carcinoma Based on Tissue Microarray Digital Analysis. Anticancer Res. 2017 Oct;37(10):5521-5524
  12. Mastronikolis NS, Tsiambas E, Fotiades PP, et al. Numerical Imbalances of Chromosome 7 in Oral Squamous Cell Carcinoma. Anticancer Res. 2018 Apr;38(4):2339-2342.
  13. Mastronikolis N, Ragos V, Kyrodimos E, et al. Mechanisms of C-myc oncogenic activity in head and neck squamous cell carcinoma. J BUON 2019; 24(6): 2242-2244
  14. Tsiambas E , Mastronikolis N, Fotiades P, et al. c-Jun/c-Fos complex in laryngeal squamous cell carcinoma JBUON 2020; 25(2): 618-620
  15. Chrysovergis A, Papanikolaou V, Mastronikolis N, et al. Chromosome 17 in Situ Hybridization Grid-Based Analysis in Oral Squamous Cell Carcinoma. Anticancer Res 2020 Jul;40(7):3759-3764