School of Medicine
University of Patras
>University of Patras



Sector: Division of Internal Medicine Ι

Clinic/Laboratory: Department of Internal Medicine

Knowledge Subject: Internal Medicine - Gastroenterology

Research Area: Gastroenterology Upper and lower Gastrointestinal bleeding Intestinal permeability ( intestinal tight junctions’ expression and bacterial translocation in patients with liver cirrhosis ) Choledocholethiasis natural history and recurrence Gastroesophageal reflux disease Hepatology Portal hypertension and variceal bleeding Choledocholethiasis natural history and recurrence Cirrhosis and the role of adipokines Cirrhosis and the role of vitamin D

University Hospital of Patras 26500 Rion - Greece 5th, Dep. of Gastroenterology

0030-2610999518, 0030-6974009799, 0030-2610422287 0030-2610992861

Summary of Curriculum Vitae

Athens University M.D 1966-73 Medicine
University of Duesseldorf - Germany Ph.D. 1983 Medicine

Positions and Employment
1975-1977 : Fellow in Internal Medicine. Department of Internal Medicine, Kreis Krankenhaus, Kirchen, West Germany
1977- 1978 : Fellow in Internal Medicine, Department of Internal Medicine, Bethesda Krankenhaus, Duisburg, West Germany
1979-1982 Fellow in Gastroenterology, Division of Gastroenterology, Bethesda Krankenhaus, Duisburg, West Germany
1982 Fellow in Roentgen Department, Bethesda Krankenhaus, West Germany
1983- 1988 Consultant and Director of the Division of Gastroenterology, Department  of Internal Medicine,  Patras University Medical School.
1988- 1998   Assistant Professor of Medicine , Department of Internal Medicine,
 Patras University Medical School. Director of the Division of Gastroenterology.
3/5/1995-31/10/1995 Visiting Scientist, Royal Free Hospital, Liver Unit, London.
1999-2004 Associate Professor of Medicine, Department of Internal Medicine, Patras University Medical School. Director of the Division of Gastroenterology
2005- 2013: Professor of Gastroenterology. Director of Gastroenterology Division, Department of Internal Medicine, Patras University Medical School. Patras, Greece.

Undergraduate Courses

Selected Publications

Thomopoulos K, Katsakoulis E, Margaritis V, Mimidis K. Vagianos C, Nikolopoulou V. Seasonality in the prevalence of acute upper gastrointestinal   bleeding.
J Clin Gastroenterol 1997 ; 25 ( 4 ) : 576 – 579
2. D. Patch, Nikolopoulou V, Mc Cormick P, Dick R, Armonis A, Wannamethee, Burroughs A.Factors related to early mortality after transjugular intrahepatic portosystemic shunt for failed endoscopic therapy in acute variceal bleeding.
Journal of Hepatology 1998 ; 28 : 453 –460.
3. K. P. Mimidis, C.Karatza, K.V Spiropoulos, T . Toulgaridis, N.A Charokopos,  K. Thomopoulos, V.Margariths, V.Nikolopoulou.
Prevalence of intrapulmonary vascular dilatations in normoxaemic patients with early liver cirrhosis.
Scand J Gstroenterol 1998 ; 33 : 998 - 992.
4. K.Thomopoulos, J. A. Mitropoulos, E. Katsakoulis, C.E Vagianos, K.Mimidis, M. Chatziargyriou, VN. Nikolopoulou.
Factors associated with failure of endoscopic injection haemostasis in bleeding peptic ulcers.
Scand J Gastroenterol 2001 ; 36 : 664 – 668.
5 K.C Thomopoulos, C. Labropoulou – Karatza, K.P Mimidis, E.C. Katsakoulis, G. Ikonomou, V.N . Nikolopoulou.
Non – invasive predictors of the presence of large oesophageal varices in patients with cirrhosis.
Digestive and Liver disease 2003 ; 35 : 473 – 478.
6.  K.C Thomopoulos, G.J.Theocharis, K.A.Vagenas, D.D.Danikas, C.E.Vagianos, V.N. Nikolopoulou. Predictors of hemostatic failure after adrenaline injection in patients with peptic ulcers with non-bleeding visible vessel.
 Scand Journal of Gastroenterol 2004 Jun; 39(6):600-4
7.  Cholongitas E. Senzolo M, Kwong K, Nikolopoulou V, Leonardo G, Shaw S, Burroughs AK.
 Risk factors, sequential organ failure assessment and model for end-stage liver disease scores for predicting short term mortality in cirrhotic patients admitted to intensive care unit.
 Aliment Pharmacol Ther. 2006 Apr 1;23(7):883-93.
8. Thomopoulos K, Theocharis G, Mimidis K, Lampropoulou – Karatza Ch, Alexandridis E, Nikolopoulou V.
 Improved survival of patients presenting with acute variceal bleeding. Prognostic indicators of short – and long-term mortality.
 Dig Liver Dis. 2006 Dec;38(12):899-904. Epub 2006 Sep 26.
9. Thomopoulos KC, Pagoni NA, Vagenas KA, Margaritis VG, Theocharis GI, Nikolopoulou V.
 Twenty-four hour prophylaxis with increased dosage of octrotide reduces the incidence of post-ERCP pancreatitis.
 Gastrointest Endosc. 2006 Nov;64(5):726-31.
10. Theocharis GJ, Thomopoulos  KC, Sakellaropoulos G, Katsakoulis E, Nikolopoulou V. Changing  trends in the epidemiology and clinical outcome of acute upper gastrointestinal bleeding in a defined geographical area in Greece.
J Clin Gastroenterol. 2008 Feb;42(2):128-33.
11.  Τriantos CK, Nikolopoulou V, Burroughs AK. Review article: the therapeutic and prognostic benefit of portal pressure reduction in cirrhosis. Aliment Pharmacol Ther. 2008 Oct 15;28(8):943-52.
12. Giannikoulis C, Karkoulias K, Thomopoulos K, Marangos M, Spiropoulos K, Nikolopoulou V. Patients with gastroesophageal reflux disease and respiratory manifestations do not present lung function disorders during cardiopulmonary exercise test. Dis Esophagus. 2011 Apr;24(3):189-93.
13. Chronis A, Thomopoulos K, Sapountzis A, Triantos C, Kalafateli M, Kalofonos C, Nikolopoulou V. Adiposity factors are not related to the presence of colorectal adenomas. Clin Exp Gastroenterol. 2011;4:257-61
14. Assimakopoulos SF, Tsamandas AC, Tsiaoussis GI, Karatza E, Triantos C, Vagianos CE, Spiliopoulou I, Kaltezioti V, Charonis A, Nikolopoulou VN, Scopa CD, Thomopoulos KC.  Altered intestinal tight junctions' expression in patients with liver cirrhosis: a pathogenetic mechanism of intestinal hyperpermeability. Eur J Clin Invest. 2012 Apr;42(4):439-46
15. Kalafateli m, Triantos CK, Nikolopoulou V, Burroughs A. Non- variceal gastrointestinal bleeding in patients with liver cirrhosis : a review
Dig Dis Sci 2012 , 57: 2743-54.