School of Medicine
University of Patras
>University of Patras



Sector: Division of Clinical Laboratories

Clinic/Laboratory: Department of Nuclear Medicine

Knowledge Subject: Nuclear Medicine

Research Area: Clinical applications of SPECT/CT, parathyroid imaging, techniques for noise reduction of scintigraphic images

Department of Nuclear Medicine, University Hospital of Patras, Rion Patras 26504, Greece Building D, level 2

+30 2610 999210 +30 2610 994470

Summary of Curriculum Vitae

Dr. Apostolopoulos was born in Patras, Greece, in 1960. He received his MD in 1984 from the Medical School of the University of Athens and his Doctorate from the same University in 1989. He completed his specialization in Nuclear Medicine in the “Aretaieion” Hospital, Athens. He was trained in Nuclear Cardiology in the University Hospital “Haut-Leveque”, Bordeaux, France in 1988. In January 2010 he joined the Medical PET of the German Cancer Research Centre (Deutsches Krebsforschung Zentrum, DKFZ), Heidelberg, Germany, as participant in a research project. His special interests are in Classical Nuclear Medicine, particularly in the fields of Nuclear Cardiology, Endocrinology and Oncology. His research work is mainly on the clinical applications of SPECT/CT, parathyroid imaging and techniques for noise reduction of scintigraphic images. He has co-authored in 37 scientific papers published in peer-reviewed medical journals and in 68 oral/poster presentations in European or International Congresses. His publications have 194 citations (h-index=7). He is a co-investigator in 3 grants. He has given aapproximately 60 lectures in Medical Congresses and CME sessions of various Medical Associations. He has co-edited the book “Introduction to Nuclear Medicine” for the students of the University of Patras, and co-authored the chapter “Radioisotopic techniques in obstructive uropathy” in the book “Endoscopic Urology”, by E.N. Liatsikos and J-U Stolzenburg. He is a reviewer in two Medline-indexed medical journals. He is supervising 5 PhD dissertations.

Undergraduate Courses

Postgraduate Courses

Interdepartmental Postgraduate Course in Medical Physics. Topic: Principles of Nuclear Medicine.

Selected Publications

  1. Apostolopoulos DJ, Houstoulaki E, Giannakenas C, Alexandrides T, Spiliotis J, Nikiforidis G, Vlachojannis JG, Vassilakos. PJ. 99m-Tc-Tetrofosmin for Parathyroid Scintigraphy: Comparison to Thallium-Technetium Scanning. J Nucl Med. 1998;39:1433-41.
  2. Hahalis G, Manolis AS, Apostolopoulos D, Alexopoulos D, Vagenakis AG, Zoubos NC. Right ventricular cardiomyopathy in beta-thalassaemia major. Eur Heart J. 2002; 23:147-156.
  3. Hahalis G, Stathopoulos C, Apostolopoulos D, Vassilakos P, Alexopoulos D, Manolis A.S. Contribution of the ST elevation/T wave normalization in Q-wave leads during routine, pre-discharge treadmill exercise test to patient management and risk stratification after acute myocardial infarction. A 2.5 year follow-up study. J Am Coll Cardiol. (JACC) 2002;40:62-70.
  4. Apostolopoulos DJ, Spyridonidis TJ, Giannakenas CC, Adamopoulos CJ, Alexandrides TK, Vassilakos PJ. Parathyroid scintigraphy with 99mTc-Sestamibi and 99mTc-Tetrofosmin: Comparison of diagnostic efficacy and kinetics. World J Nucl Med. 2003;2:182-190.
  5. Alexandrides TK, Kouloubi K, Vagenakis AG, Yarmenitis S, Spyridonidis T, Vassilakos P, Apostolopoulos D. The value of scintigraphy and ultrasonography in the preoperative localization of parathyroid glands in patients with primary hyperparathyroidism and concomitant thyroid disease. Hormones (Athens). 2006;5:42-51.
  6. Apostolopoulos DJ, Spyridonidis T, Skouras T, Giannakenas C, Savvopoulos C, Vassilakos PJ. Comparison between 1800 and 3600 acquisition arcs with and without correction by CT-based attenuation maps in normal hearts at rest. Nucl Med Commun. 2008;29:110-9.
  7. Markou KB, Tsekouras A, Anastasiou E, Vlassopoulou B, Koukkou E, Vagenakis GA, Mylonas P, Vasilopoulos C, Theodoropoulou A, Rottstein L, Lampropoulou E, Apostolopoulos D, Jabarov R, Vagenakis AG, Georgopoulos NA. Treating iodine deficiency: long-term effects of iodine repletion on growth and pubertal development in school-age children. Thyroid. 2008;8:449-54.
  8. Skiadopoulos S, Karatrantou A, Korfiatis P, Costaridou L, Vassilakos P, Apostolopoulos D, Panayiotakis G. Evaluating image denoising methods in myocardial perfusion single photon emission computed tomography (SPECT) imaging. Meas. Sci. Technol. 20 (2009) 104023 (11pp).
  9. Apostolopoulos DJ, Papandrianos NI., Symeonidis A, Spyridonidis T, Alexiou S, Zampakis P, Savvopoulos C, Vassilakos PJ, Matsouka P. Technetium-99m Depreotide Imaging by Single Photon Emission Tomography/Low Resolution Computed Tomography in Malignant Lymphomas. Comparison with Gallium-67 Citrate. Ann Nucl Med. 2010;24:639-47.
  10. Apostolopoulos DJ, Dimitrakopoulou-Strauss A, Hohenberger P, Roumia S, Strauss LG. Parametric images via dynamic 18F-fluorodeoxyglucose positron emission tomographic data acquisition in predicting midterm outcome of liver metastases secondary to gastrointestinal stromal tumours. Eur J Nucl Med Mol Imaging. 2011;38:1212-23.
  11. Spyridonidis T, Patsouras N, Alexiou S, Apostolopoulos DJ. Imaging myocardial inflammation of various etiologies with (99m)Tc-depreotide SPET/CT. Hell J Nucl Med. 2011;14:260-3.
  12. Apostolopoulos DJ, Davlouros P, Alexiou S, Patsouras N, Spyridonidis T, Vassilakos PJ, Alexopoulos D. ST-segment depression during vasodilator stress is of minor clinical importance in females with normal myocardial perfusion imaging and low or intermediate risk of coronary artery disease. Eur J Nucl Med Mol Imaging. 2012;39:437-45.
  13. Spyridonidis TJ, Apostolopoulos DJ. Is there a role for Nuclear Medicine in diagnosis and management of patients with primary aldosteronism? Hell J Nucl Med. 2013 May-Aug;16(2):134-9.
  14. Spyridonidis TJ, Matsouka P, Symeonidis A, Savvopoulos C, Vassilakos PJ, Apostolopoulos DJ. 99mTc Sestamibi as a Prognostic Factor of Response to First-Line Therapy and Outcome in Patients With Malignant Lymphoma. Clin Nucl Med. 2013 Oct 1. [Epub ahead of print]