MICHAIL GEORGE, Associate Professor

Department of Obstetrics - Gynecology, School of Medicine, University of Patras, Rion, 26504, Greece Obs/Gynae Outpatients, Ground Floor, Patras University Hospital

gmichail@upatras.gr

Office hours

Summary of Curriculum Vitae

Mr George Michail MD PhD received his Medical Degree from the Medical School of the Kapodistrian University of Athens, Greece. He trained in the Obstetrics and Gynecology Department of the Patras University Hospital, Greece, receiving the Obstetrician-Gynecologist title in 2005. In 2006, he started his Subspecialty Training in Dublin, Ireland, as Clinical Research Fellow in the Obs/Gynae Department of the Royal College of Surgeons in Ireland and trained in Colposcopy close to Professor Walter Prendiville (LLETZ procedure inventor), he was then accredited with the British Society of Colposcopy and Cervical Pathology (B.S.C.C.P.) Diagnosis & Treatment Diploma following exams. Later, in 2007 he presented his PhD Thesis at Patras University Medical School. Qualified as a B.S.C.C.P. Trainer in Colposcopy since 2015, he has successfully submitted audit for several re-accreditation rounds, while also attending numerous B.S.C.C.P. “Training the Trainers” seminars. Since 2010 he has established and operated as the lead colposcopist and surgeon the Dysplasia/Colposcopy Outpatient Clinic in Patras University Hospital, a division servicing numerous patient referrals from Southwestern Greece.

His current placement is within the Academic staff of Patras University Medical School Obstetrics and Gynecology Department (2013, Senior Lecturer - 2020, Assistant Professor - 2024, Associate Professor), while also serving as Consultant Obstetrician/Gynecologist in the Obs/Gyne ward of Patras University Hospital, Rion, Greece. He has co-supervised to completion several PhD and MSc candidates.

His expertise focusses on Cervical Pathology, HPV vaccination, cervical cancer screening & prevention, self-sampling approaches for cervical screening, HPV latency and gynecologic oncology.

With a commitment to promoting HPV vaccination implementation and cervical cancer screening in Greece, he has participated in several expert scientific committees and educational webinars, besides delivering numerous invited related lectures in keynote national Congresses and venues since 2013. Being an active member of the Greek colposcopic society, he has contributed to the development of numerous national and multinational collaborative scientific protocols in HPV related disease, HPV vaccination, self-sampling approaches for cervical screening. He has also served for several years as an elected member of the Executive Board of the Hellenic Society for Colposcopy and Cervical Pathology (H.S.C.C.P.).

Undergraduate Courses

• Obstetrics & Gynaecology (Semester: 9th & 10th)
• Gynaecology - Obstetrics (Semester: 7th)
• Obstetrics – Gynaecology (Clinical Training) (Semester: 11th & 12th)

Selected Publications

1. Daponte A, Michail G, Daponte AI, et al. Urine HPV in the context of genital and cervical cancer screening – an update of current literature. Cancers 2021; 13(7), 1640.

2. Daponte N, Valasoulis G, Michail G, et al. HPV-Based Self-Sampling in Cervical Cancer Screening: An Updated Review of the Current Evidence in the Literature. Cancers (Basel). 2023 Mar 8;15(6):1669.

3. Valasoulis G, Pouliakis A, Michail G, et al. Alterations of HPV-Related Biomarkers after Prophylactic HPV Vaccination. A Prospective Pilot Observational Study in Greek Women. Cancers (Basel). 2020; 12(5):1164.

4. Agorastos T, Chatzistamatiou K, Tsertanidou A, et al. Implementation of HPV-based cervical cancer screening combined with self-sampling using a midwifery network across rural Greece. The GRECOSELF study. Cancer Prev Res 2019; 12(10):701-710.

5. Michail G, Smaili M, Vozikis A, et al. Female students receiving post-secondary education in Greece: the results of a collaborative human papillomavirus knowledge survey. Public Health. 2014; 128(12):1099-105.

6. Chatzistamatiou K, Vrekoussis T, Tsertanidou A, et al. Acceptability of Self-Sampling for Human Papillomavirus-Based Cervical Cancer Screening. J Womens Health (Larchmt). 2020; 29(11):1447-1456.

7. Michail G, Karahaliou A, Skiadopoulos S, et al. Texture analysis of perimenopausal and post-menopausal endometrial tissue in grayscale transvaginal ultrasonography. British Journal of Radiology 2007; 80(956): 609-16.

Contribution in Books/Book Chapters:

1. Karahaliou A, Skiadopoulos S, Michail G, Kalogeropoulou C, Boniatis I, Kourounis G, Panayiotakis G, Costaridou L. Textyre Analysis for classification of endomtrial tissue in gray scale transvaginal ultrasonography. in "IFIP International Federation for Information Processing", Volume 204, Artificial Intelligence Applications and Innovations, eds. Maglogiannis, I., Karpouzis, K., Bramer, M., (Boston: Springer), 2006, pp. 713-721.

2. Michail G. Endometrial Cancer – Diagnosis. Special Issue on "Endometrial Cancer: Pathogenesis, Diagnosis and Treatment" Int J Clin Ther Diagn. S1:005 17-27 SciDoc Publishers, ISSN 2332-2926.

3. Androutsopoulos G, Karnabatidis D, Michail G, Decavalas G. Uterine artery embolization as an alternative to hysterectomy, in patients with uterine myomas. Approaches to hysterectomy, InTech 2015:35-47. ISBN 978-953-51-2199-2.

4. Pouliakis A, Margari N, Karakitsou E, Pergialiotis V, Valasoulis G, Michail G, Damaskou V, Panayiotides IG. Artificial Intelligence and Image Analysis for the Identification of Endometrial Malignancies: A Comparative Study. Book: “Quality Assurance in the Era of Individualized Medicine”. Editor: Anastasius S. Moumtzoglou. IGI Global Publishers, November 2019 DOI: 10.4018/978-1-7998-2390-2.ch005. ISBN13: 9781799823902

5. Pouliakis A, Valasoulis G, Michail G, Salamalekis E, Margari N, Kottaridi C, Spathis A, Karakitsou E, Gouloumi AR, Leventakou D, Chrelias G, Nasioutziki M, Kyrgiou M, Dinas K, Paraskevaidis E, Chrelias Ch, Daponte A, Panayiotides IG. New Aspects and an Artificial Intelligence Approach for the Detection of Cervical Abnormalities in the Covid-19 Pandemic Era. Book: “Quality of Healthcare in the Aftermath of the COVID-19 Pandemic” Εditors: Anastasius S. Moumtzoglou. IGI Global Publishers, December 2021 DOI: 10.4018/978-1-7998-9198-7.ch011. ISBN13: 9781799891987

6. Androutsopoulos G, Styliara I, Zarogianni E, Michail G, Adonakis G. Is It Time to Reconsider the Clinical Role of ErbB Targeted Therapy in Endometrial Cancer? Book “Endometrial cancer. Current Epidemiology, Detection and Management” 2nd Edition, Editors: Samir A Farghaly. Series: Obstetrics & Gynecology Advances Nova Science Publishers, November 2022. DOI: 10.52305/XDFN1391. ISBN979-8-88697-405-8 (eBook).

Selected Presentations

Invited Lectures from 2020 onwards:

"HPV Vaccines", Lecture at the Conference "Women and Cancer, from prevention to treatment", organized by the Oncological Research Society (EOGE) and the Oncology Department of the Patras University Hospital (Hybrid event-Live & Web conduct). Patras, October 9-10, 2020.

“HPV Vaccination – New Horizons”, Lecture at the Conference “Cervical Pathology & Colposcopy: Cytology – Biomarkers – Colposcopy – Histology & Further Management – Case Presentation”, organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. (Web Conduct). Ioannina, October 30-November 1, 2020.

“The New Cervical Pathology Software and Risk Assessment Perspective”, Presentation at the Conference “Cervical Pathology & Colposcopy: Cytology – Biomarkers – Colposcopy – Histology & Further Management – Case Presentation”, organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. (Web Conduct). Ioannina, October 30-November 1, 2020.

"Changing the prognostic model for cervical cancer", Lecture at the Conference "9th Panhellenic Conference HPV infection & related diseases", organized by the Hellenic Society for Research and Treatment of the Papilloma Virus (Web Conduct). Thessaloniki, May 28-30, 2021.

"Latest data on HPV vaccination", Lecture at the Conference "Latest developments in HPV & biomarkers in Obstetrics & Gynecology No 6", organized by the Women's Health Care Society of Greece in collaboration with the Obstetrics-Gynecology Clinic of the University of Thessaly. (Hybrid event-Live & Web conduct). Larissa, October 22-24, 2021.

"HPV vaccination following conization", Lecture at the Seminar "The specialist knowledge next to the gynecologist and the woman", organized by the Colposcopy Department and the Lower Genital System Laser Applications Department of "MITERA" Maternity Hospital. (Hybrid event-Live & Web conduct). Athens, October 23, 2021.

"New perspectives in the prevention of HPV-related diseases", Lecture at the Conference "Cervical Pathology & Colposcopy: Cytology - Biomarkers - Colposcopy - Histology & Further Management - Presentation of Cases", organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. (Hybrid event-Live & Web conduct). Ioannina, November 5-7, 2021.

“Modern Application of Cervical Pathology Software”, Presentation at the Conference “Cervical Pathology & Colposcopy: Cytology – Biomarkers – Colposcopy – Histology & Further Management – Case Presentation”, organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. (Hybrid event -Live & Web conduct). Ioannina, October 30-November 1, 2021.

"Preinvasive diseases of the vulva – Current guidelines", Lecture at the "Guidelines and reality: Dilemmas in Gynecological Oncology & Menopause" venue, organized by the 3rd Obstetrics-Gynecology Clinic of Aristotle University of Thessaloniki (Web Conduct). Thessaloniki, November 19-21, 2021.

"Natural history of HPV carcinogenesis - from the anorectal region to the oropharynx.", Lecture at the "Infections & Inflammations in Obstetrics - Gynecology" venue, which was organized by the Institute of Gynecological Oncology & Mammology in collaboration with the 2nd Obstetrics-Gynecology Clinic of Aristotle University of Thessaloniki (Hybrid event-Live & Web conduct). Thessaloniki, March 12, 2022.

"Application of colposcopic algorithms and scoring for quality assurance", Lecture at the "5th Panhellenic Scientific Conference of Obstetrics and Gynecology", which was organized by the Association of Obstetricians and Gynecologists of Greece, in collaboration with RCOG & EBCOG. Athens, September 8-11, 2022.

"HPV infection in childhood and adolescence", Lecture at the "7th Panhellenic Conference of Pediatric & Adolescent Gynecology", organized by the Hellenic Society of Pediatric & Adolescent Gynecology. Patras, September 23-25, 2022.

"Cervical Cancer Screening - recent developments in Greece", Lecture at the "29th Special Session of the Hellenic Society of Obstetrics and Gynecology", which was organized by the Hellenic Society of Obsterics & Gynecology. Larissa, October 7-9, 2022.

"New screening protocols for the prevention of cervical cancer in Europe and America", Lecture at the "3rd Panhellenic conference on diseases of the female lower genitourinary system and the anal area", which was organized by the Hellenic Society for the Study of Diseases of the Lower Genital of the Woman (EKGE). Athens, 21-23 October 2022.

"HPV vaccination for boys & girls, after initiation of coitarche or after conization", Lecture at the Scientific Conference: "Cervical Pathology", which was organized by the Department of Colposcopy and Cervical Pathology IASO Maternity Hospital in collaboration with the Hellenic Society of Colposcopy and Cervical Pathology. Athens, February 18, 2023.

“Cytology, HPV-DNA or mRNA for cervical screening? What is the ultimate advantage?", Lecture at the Conference "Problems and contradictions in modern Gynecological Oncology", which was organized by the Institute of Gynecological Oncology & Mammology in collaboration with the 2nd Obstetrics-Gynecology Clinic of Aristotle University of Thessaloniki. Thessaloniki, March 17-19, 2023.

"HPV vaccination: safety and efficacy", Lecture at the "3rd Panhellenic Conference Present and Future in Oncology", which was organized by the Hellenic Society of Geriatric Oncology in collaboration with the Oncology Department of the Pathology Clinic of the University Hospital of Patras. Patras, June 9-11, 2023.

"Cervical intraepithelial neoplasia and prevention of cervical cancer", Lecture at the "30th Special Session of the Hellenic Society of Obstetrics and Gynecology", which was organized by the Hellenic Society of Obstetrics & Gynecology (EMGE). Patras, June 16-18, 2023.

“HPV vaccine - what's new?” Lecture in the “5th European Congress of the International Society of Infections in Obstetrics & Gynecology (5th ISIDOG)". Athens, Greece, October 19-22, 2023.

“The Anticipated Benefits of HPV Vaccination”, Lecture at the “Cervical Pathology & Colposcopy: Cytology – Biomarkers – Colposcopy – Histology & Further Management – Case Presentation” Conference, jointly organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. Ioannina, October 20-22, 2023.

"Latest bibliographic data from the use of HPV DNA and related HPV biomarkers", Lecture at the Conference "Newest developments in HPV & biomarkers in Obstetrics & Gynecology No. 7", organized by the Women's Health Care Society of Greece in collaboration with the Obstetrics-Gynecology Clinic of University of Thessaly. Larissa, December 15-17, 2023.

"9valent HPV vaccine in Greece in 2023: Vaccinating boys and girls against HPV", Lecture at the Conference "Newest developments in HPV & biomarkers in Obstetrics & Gynecology No 7", organized by the Women's Health Care Society of Greece in collaboration with Obstetrics-Gynecology Clinic of the University of Thessaly. Larissa, December 15-17, 2023.

“HPV Vaccination: Latest data and indications", Lecture at the Scientific Conference: "Cervical pathology: HPV tests, biomarkers, algorithms, colposcopy & scoring system in screening and triage", which was organized by the Department of Colposcopy and Cervical Pathology IASO Maternity Hospital. Athens, February 17, 2024.

"Management of cervical pathology in menopause: Prevention of unfavorable outcomes", Lecture at the Post-Training Conference "Prevention in Obstetrics and Gynecology", which was organized by the Institute of Gynecological Oncology & Mammology in collaboration with the 2nd Obstetrics-Gynecology Clinic of Aristotle University of Thessaloniki. Thessaloniki, March 29-31, 2024.

"Burden of HPV-related diseases in the anorectal tract and their prevention through vaccination", Satellite Lecture at the "2nd Athens Coloproctology Meeting on Rectal and Anal Cancer", which was organized by the Greek Society of Coloproctology. Athens, April 5-6, 2024.

"HPV Vaccination: Update", Lecture at the Seminar "Basic Principles of Colposcopy and Cervical Pathology", which was organized by the Hellenic Cervical Pathology Study Group HECPA and the Hellenic Society of Colposcopy and Cervical Pathology under the auspices of the European Society of Colposcopy (EFC). Athens, April 12-13, 2024.

"Vaccination after CIN treatment", Lecture at the 16th Panhellenic Obstetrics-Gynecology Conference, organized by the Hellenic Society of Obstetrics & Gynecology (EMGE). Ioannina, June 13-16, 2024.

"Molecular testing of cervical cancer biomarkers in self-sampling samples", Lecture at the Conference "Developments & Latest Data in Prevention in Obstetrics & Gynecology" - "HPV & BIOMARKERS No8", organized by the Women's Health Care Society of Greece in collaboration with the Obstetrics-Gynecology Clinic of the University of Thessaly. Larissa, September 20-21, 2024.

"HPV vaccination: Current standing", Lecture in the "Public Health Issues-Anti-Cancer Society of Ioannina" section: of the Conference "Cervical Pathology & Colposcopy: Cytology - Biomarkers - Colposcopy - Histology & Further Management - Presentation of Cases", organized by H.S.C.C.P. & the HECPA Group, the Hellenic Society of Clinical Cytology and the Hellenic Society of Pathological Anatomy. Ioannina, October 17-20, 2024.

"HPV vaccine - Guidelines", Lecture at the Conference: "Guidelines & Reality - Dilemmas in the daily practice of obstetrics and gynecology", which was organized by the 3rd Obstetrics-Gynecology Clinic of Aristotle University of Thessaloniki & the Medical Society of Thessaloniki. Thessaloniki, November 1-3, 2024.

“CIN management – European & UK guidelines” Lecture at the "4th Panhellenic conference on diseases of the female lower genitourinary system and the anal area", which was organized by the Hellenic Society for the Study of Diseases of the Lower Genital of the Woman (EKGE). Athens, 22-24 November 2022.

PhD Theses Advisor

Doctoral Dissertations:

1. Member of the Examining Committee in the Doctoral Dissertation of Obstetrician-Gynecologist Ms. Elpiniki Chronopoulou: "The role of WNT b-catenin in early fetal development & miscarriages in the first trimester" (Department of Medicine, University of Patras 824/4-4- 2022); thesis was supported on May 3, 2022

2. Member of the Examining Committee in the Doctoral Dissertation of the Obstetrician-Gynecologist Ms. Dimitras Mantzou: "The contribution of genetic and mental factors to the sexuality of women with polycystic ovary syndrome (PCOS)" (Department of Medicine, University of Patras 840/17-10-2022); thesis was supported on March 18, 2023.

3. Member of the Examining Committee in the Doctoral Dissertation of Obstetrician-Gynecologist Ms. Efthymia Papakonstantinou: "The role of post-translational modifications of histones and DNA methylation in ovarian cancer" (Department of Medicine, University of Patras 877/6-11- 2024); thesis was supported on July 16, 2024.

4. Member of the Examining Committee in the Doctoral Dissertation of the Obstetrician-Gynecologist Mr. Theodoros Filindris: "The role of GnRH-a administration in the angiogenesis of endometriosis" (Department of Medicine, University of Patras 891/22-4-2024); thesis was supported on May 28, 2024.

5. Member of the Examining Committee in the Doctoral Dissertation of the Obstetrician-Gynecologist Ms. Ioulia Magaliou: "Prospective observational study of expression of HPV-related biomarkers and cervical infections in women of reproductive age with cervical dysplasia referred for colposcopy & further management in the post-Covid era", of the Department of Obstetrics of the School of Health Sciences of the University of Western Macedonia. No. Register: 11, audited by Assoc. Professor Mr. Dimitrios Papoutsis. Dissertation start date: 17 March 2022 (not yet accomplished).

Master Thesis:

1. Member of the Examining Committee in the Master's Thesis of Pharmacist Ms. Afrodite Moumouri: "Preventive analgesic treatment in gynecological patients undergoing diagnostic colposcopy", in the framework of the Master's Degree in Clinical Pharmacy - Pharmacotherapy of the Department of Pharmacy of Patras University; this work was presented on December 5, 2016.

2. Member of the Examining Committee in the Master's Diploma Thesis of psychologist Ms. Vasiliki Paloumpi: "Knowledge and opinions of the students of the University of Patras regarding HPV", in the context of the Master's Program "Public Health" of the Department of Medicine of Patras University; this work was presented on February 9, 2017.

3. Member of the Examining Committee in the Master's Thesis of General Practitioner Mr. Dionysis Adraktas: "Overall evaluation of the screening program for cervical cancer 2011-2015 in the prefecture of Gastouni Health Center", within the framework of the Public Health Master's Degree of the Department of Medicine of Patras University; this work was presented on May 30, 2017.

4. Member of the Examining Committee in the Master's Thesis of Obstetrician-Gynecologist Ms. Dimitra Xenaki: "Knowledge, attitudes and behaviors of teachers and health professionals, for the prevention of human papillomavirus (HPV)", within the framework of the "Public Health" Master's Program of the Department of Medicine of Patras University; this work was presented on February 8, 2018.

5. Member of the Examining Committee in the Master's Thesis of Midwife Ms. Georgia Papanikou: "Investigation of knowledge and attitudes of post-adolescent youths regarding sexually transmitted diseases and contraception in the area of Patras", within the framework of the "Public Health" Master's Program of the Department of Medicine of Patras University; this work was presented on October 18, 2019.

6. Member of the Examining Committee in the Master's Thesis of Midwife Ms.Maria Paraskevopoulou: “Assessment of the effect of curcumine in HPV-induced precancerous lesions”, in the framework of the interdisciplinary Postgraduate Study Program "Medicinal Chemistry: Design and Development of Pharmaceutical Products" of the Department of Chemistry of Patras University; this work was presented on August 30, 2021.

7. Member of the Examining Committee in the Master's Thesis of Obstetrician-Gynecologist Ms. Narges Shohreh Farsian “RCT with placebo for the evaluation of the efficacy of pulsed electomanetic field therapy in menstrual pain” in the Department of Pharmacy of Patras University (academic year 2021-2022); this work was presented on September 6, 2022.

8. Supervisor within the Three-Member Examining Committee in the Diploma Thesis of Obstetrician-Gynecologist Ms. Fygalia Nika “Vitamin D levels in the third trimester of pregnancy and association with prematurity and other pregnancy complications”; in the Department of Obstetrics of the University of West Attica (academic year 2023-2024); this work was presented on March 6, 2024.

Other Activities

Involvement in Scientific Webinars:

“ASCCP Guidelines on the management of precancerous cervical pathology” Presentation in SESSION 1: CERVICAL PATHOLOGY of “The Thessaloniki Webinar on Guidelines of Gynecological Cancer management”, organized by the 2nd Dept of Obstetrics & Gynecology of Aristotle University of Thessaloniki, February 19, 2022.

"The real disease burden of HPV-related diseases", Presentation at the 11th Meeting of the Hellenic HPV Society (hpvsociety)], in conjunction with the 3rd Conference of Implementation Support Agencies of the Strategy of World Health Organization for the elimination of cervical cancer in Greece. Thessaloniki, June 10, 2023.

"Adult HPV vaccination", presentation in the PERCH Greek Action Plan, in the context of the 2025 European Week for cervical cancer prevention, organized by the 1st Health Prefecture of Attica, January 21, 2025.

Moderator in the 1st EFC Interactive Learning Webinar for Colposcopists 2025 "Long term outcomes following treatment of CIN: Obstetric Prematurity and Treatment Failures" February 12, 2025.