Clinical Neuroanatomy – Molecular Anatomy
Semester 5th ()
Hours Teaching 2 hours, Laboratory 0 hours, Tutorial 0 hours , Clinical Training 0 hours (per week)
Teachers
Description
Molecular Anatomy: Objectives and goals
- The systematic presentation of the normal molecular profile of human cells/tissues and organs during embryogenesis and adult life and the integration of knowledge regarding the structure/composition of the human body in the macroscopic, microscopic, ultrastructural and molecular level.
- Linking the knowledge of the macroscopic, microscopic and molecular anatomy with physiology and pathology of human diseases leading thus to the better understanding of pathophysiology, pathogenesis, microscopic, ultrastructural and molecular alterations of common and important human diseases.
Clinical Neuroanatomy: Objectives and goals
Linking macroscopic anatomy of the Nervous System with the pathophysiology, clinical presentation and molecular pathogenesis of common neurological and psychiatric diseases.
Course detailed description-Contents
The two hours weakly course of Molecular Anatomy-Clinical Neuroanatomy includes lectures from faculty members’ coordinators and invited speakers and scientific presentations by the students (small projects/small working groups) and practice in methods commonly applied to human tissue material.
Molecular Anatomy contents
- Molecular Developmental Anatomy-Study of the molecular profile of cells and tissues in the human embryo during histogenesis/organogenesis -Correlation with developmental and adult human diseases.
- Molecular Anatomy of human cells/tissues and organs. Integration of knowledge regarding the structure/composition of the adult human body in the macroscopic, microscopic ultrastructural and molecular level. Association of normal molecular anatomy with pathophysiology, pathogenesis, microscopic, ultrastructural and molecular alterations of common and important human diseases. For example:
- Molecular anatomy of epithelial tissue-Human disorders of tight junctions, desmosomes, adherence junctions, gap junctions, human disorders of cilia etc
- Molecular Anatomy of mesenchymal tissue- EMT, fibrosis and cancer
- Molecular anatomy of muscle tissue-Cardiomyopathies, myopathies etc
- Molecular Anatomy of adipose tissue-Obesity and metabolic syndrome
- Molecular Anatomy of bone and cartilage-Osteoporosis-Bone metastasis-osteoarthritis
- Molecular Anatomy of the urinary system-Glomerulopathies-Polycystic kidney disease
- Molecular anatomy of the Respiratory System-Obstructive pulmonary disease, Lung fibrosis, Lung Cancer
- Molecular Anatomy of the Liver and Pancreas-Cirrhosis, Liver and Pancreatic Cancer
- Molecular Anatomy of the Digestive Truck-Malabsorption, gastritis, colon cancer
- Molecular Anatomy of the cardiovascular system-Hypertension, atherosclerosis, angiogenesis-lymphangiogenesis and cancer
Clinical Neuroanatomy Contents
Neuroanatomical and molecular basis of: psychiatric diseases (depression, schizophrenia), stress, fear, anxiety, addiction, autism, intracranial hypertension and brain edema, brain trauma, brain vascular disease, neurodegenerative diseases (Alzheimer, Parkinson, ALS), demyelinating diseases (Multiple sclerosis), tumors of the CNS